Therapeutic Strategies

Strategies for therapeutic hypometabothermia.

Although therapeutic hypothermia and metabolic suppression have shown robust neuroprotection in experimental brain ischemia, systemic complications have limited their use in treating acute stroke patients. The core temperature and basic metabolic rate are tightly regulated and maintained in a very stable level in mammals. Simply lowering body temperature or metabolic rate is actually a brutal t...

Therapeutic Strategies in Schizophrenia

Hemangiomas - current therapeutic strategies.

Hemangiomas are benign neoplasms of the vasculature frequently encountered in children. Several studies have shown that these tumors are characterized by excessive angiogenesis. Although benign, the lesions can present with complications, and may thus require treatment. There are multiple therapeutic options available for patients with problematic or life threatening hemangiomas, some of which ...

[Therapeutic strategies in antiphospholipid syndrome].

The classical clinical picture of the antiphospholipid syndrome (APS) is characterized by venous or arterial thromboses, fetal losses and thrombocytopenia, in the presence of antiphospholipid antibodies (aPL), namely lupus anticoagulant, anticardiolipin antibodies or antibodies directed to various proteins, mainly β2 glycoprotein I, or all three. Apart from being "primary" (without any discerna...

Therapeutic strategies for rheumatoid arthritis.

It affects approximately 0.8 percent of adults worldwide, 2 is more common in women (by a ratio of 3 to 1), and has an earlier onset in women, frequently beginning in the childbearing years. 3 Recent advances in understanding the cytokine networks that are responsible for the ongoing inflammatory response in rheumatoid arthritis 4 have led to the successful use of therapies that target tumor ne...